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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9681 | MAK-683 hydrochloride | Histone Methyltransferase | |
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay. | |||
T15201 | MAK683 | Histone Methyltransferase | |
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay). | |||
T3458 | EED226 | Histone Methyltransferase | |
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM. | |||
T22322 | EEDi-5285 | UM-EEDi-5285,EEDI5285 | Histone Methyltransferase |
EEDi-5285, an orally active and highly potent inhibitor targeting embryonic ectoderm development (EED) protein, exhibits anti-cancer activity. It demonstrates exceptional efficacy with an IC50 value of 0.2 nM, indicating... | |||
T40154 | FTX-6058 | ||
FTX-6058 is a potent orally active inhibitor targeting Embryonic Ectoderm Development (EED). It effectively induces HbF protein expression in both cell and murine models. This compound holds significant potential for res... | |||
T40155 | FTX-6058 hydrochloride | ||
FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED), with the ability to induce HbF protein expression in both cell and murine models. This compound is particularly valu... | |||
T13765 | MAK683-CH2CH2COOH | Others | |
MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design EED-Targeted PROTAC which are EED degrader-1 and PROTAC EED... | |||
T61975 | Pociredir | ||
Pociredir (FTX-6058) is a potent, selective and orally active inhibitor of embryonic ectoderm development (EED) (KD= 0.163 nM). Pociredir (FTX-6058) has research value in inflammatory or hemoglobinopathies, such as sickl... | |||
T73945 | MAK683-CH2CH2COOH hydrochloride | ||
MAK683-CH2CH2COOH, targeting embryonic ectoderm development protein (EED), alongside a VHL ligand for E3 ubiquitin ligase, contributes to the formulation of PROTAC EED degrader-1 and PROTAC EED degrader-2 [1]. |